Takeda Pharmaceuticals is facing 14 lawsuits filed against the company by patients in Indiana who were diagnosed with bladder cancer after taking the diabetes drug Actos. More than 3,000 Actos bladder cancer lawsuits have been filed against Takeda on behalf of former patients or their families.
According to the Indiana Actos lawsuits, the 14 patients named in the claims were diagnosed with bladder cancer directly as a result of having taken Actos. Lawyers representing these patients and their families allege that Takeda failed to properly warn users about the link between Actos and bladder cancer.
Concerns about the risk of cancer among Actos users arose in 2011, when the Food and Drug Administration warned that the long term use of the diabetes drug made patients more likely to be diagnosed with cancer of the bladder. The FDA’s warning about Actos prompted health officials in France and Germany to recall the drug from sale in those countries.
Takeda was asked by the FDA as early as 2005 to release a warning about the side effects of Actos. Attorneys involved in the Actos lawsuits against Takeda have alleged that Takeda decided against issuing this warning because of the risks it could pose to the huge profits being generated for the company by sales of the drug. Following warnings about the health risks of another diabetes drug, Avandia, Actos became the top selling diabetes drug in the world before concerns about its risk of causing bladder cancer prompted a massive drop in sales.